Concepedia

A Novel Potent and Selective Histamine H3 Receptor Antagonist Enerisant: In Vitro Profiles, In Vivo Receptor Occupancy, and Wake-Promoting and Procognitive Effects in Rodents

Noriko Hino, Toshiyuki Marumo, Makiko Kotani, Toshiharu Shimazaki, Ayaka Kaku-Fukumoto, Hirohiko Hikichi, Jun-ichi Karasawa, Yasumitsu Tomishima, Hiroko Komiyama, Emi Tatsuda,

Journal of Pharmacology and Experimental Therapeutics · 2020 · 16 citations · 36 references

DOIFull text

Open access

Concepts

References

36

The rat brain in stereotaxic coordinates

Miklós Palkovits · Neuropeptides · 1983 · 29K citations

, , +12

Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor

Jean‐Michel Arrang, M. Garbarg, Jean‐Charles Schwartz · Nature · 1983 · 1.6K citations

, , +14

Cloning and Functional Expression of the Human Histamine H<sub>3</sub>Receptor

Timothy W. Lovenberg, Barbara Roland, Sandy J. Wilson et al. · Molecular Pharmacology · 1999 · 700 citations · Full text

, , +16

GSK189254, a Novel H3 Receptor Antagonist That Binds to Histamine H3 Receptors in Alzheimer’s Disease Brain and Improves Cognitive Performance in Preclinical Models

Andrew D. Medhurst, A.R. Atkins, I.J.M. Beresford et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 301 citations

, , +13

Identification of Rat H<sub>3</sub>Receptor Isoforms with Different Brain Expression and Signaling Properties

Guillaume Drutel, Nina Peitsaro, Kaj Karlstedt et al. · Molecular Pharmacology · 2001 · 286 citations

, , +17