Analyses of human gliomas by restriction landmark genomic scanning

A general method for isolation of high molecular weight DNA from eukaryotes

Nikolaus Blin, Darrel W. Stafford · Nucleic Acids Research · 1976 · 2.8K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

Adrian Merlo, James G. Herman, Li Mao et al. · Nature Medicine · 1995 · 2K citations

Medicine, Genetics, Molecular Biology +17

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

Towia A. Libermann, Harris R. Nusbaum, Nissim Razon et al. · Nature · 1985 · 1.5K citations

Medicine, Molecular Genetics, Oncology +12

Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers.

James G. Herman, Adrian Merlo, Li Mao et al. · PubMed · 1995 · 1.4K citations

Medicine, Genetics, Oncology +17

Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification.

Albert J. Wong, Sandra H. Bigner, Darell D. Bigner et al. · Proceedings of the National Academy of Sciences · 1987 · 850 citations · Full text

Medicine, Genetics, Oncology +10