TLR3 augments glucocorticoid-synthetic enzymes expression in epidermal keratinocytes; Implications of glucocorticoid metabolism in rosacea epidermis

Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea

Kenshi Yamasaki, Anna Di Nardo, Antonella Bardan et al. · Nature Medicine · 2007 · 840 citations

Life Sciences, Biochemistry, Immunology +13

Ultraviolet radiation damages self noncoding RNA and is detected by TLR3

Jamie J. Bernard, Christopher Cowing-Zitron, Teruaki Nakatsuji et al. · Nature Medicine · 2012 · 396 citations

Life Sciences, Immunology, Molecular Biology +5

TLR2 Expression Is Increased in Rosacea and Stimulates Enhanced Serine Protease Production by Keratinocytes

Kenshi Yamasaki, Kimberly Natee Kanada, Daniel T. MacLeod et al. · Journal of Investigative Dermatology · 2010 · 375 citations · Full text

Medicine, Dermatology, Immunology +14

ACTH receptor, CYP11A1, CYP17 and CYP21A2 genes are expressed in skin.

Gennady Ermak, Martín C. Mihm · The Journal of Clinical Endocrinology & Metabolism · 1996 · 204 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +14

Cortisol Synthesis in Epidermis Is Induced by IL-1 and Tissue Injury

S. Vukelic, Olivera Stojadinović, Irena Pastar et al. · Journal of Biological Chemistry · 2011 · 193 citations · Full text

Life Sciences, Biochemistry, Dermatology +17