GOLPH3 inhibition reverses oxaliplatin resistance of colon cancer cells via suppression of PI3K/AKT/mTOR pathway

GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer

Kenneth L. Scott, Omar Kabbarah, Mei‐Chih Liang et al. · Nature · 2009 · 353 citations · Full text

Medicine, Cancer Biology, Oncology +12

Bcl-2/Bax ratios in chronic lymphocytic leukaemia and their correlation with in vitro apoptosis and clinical resistance

Chris Pepper, T. G. Hoy, D P Bentley · British Journal of Cancer · 1997 · 234 citations · Full text

Medicine, Cell Biology, Hematology +10

Oxaliplatin resistance in colorectal cancer cells is mediated via activation of ABCG2 to alleviate ER stress induced apoptosis

Hsi‐Hsien Hsu, Ming‐Cheng Chen, Rathinasamy Baskaran et al. · Journal of Cellular Physiology · 2017 · 168 citations

Medicine, Oncology, Pharmacology +17

Establishment and characterization of models of chemotherapy resistance in colorectal cancer: Towards a predictive signature of chemoresistance

Niels F. Jensen, Jan Stenvang, Mette K. Beck et al. · Molecular Oncology · 2015 · 139 citations · Full text

Medicine, Cancer Biology, Oncology +16

Two-compartment tumor metabolism: Autophagy in the tumor microenvironment and oxidative mitochondrial metabolism (OXPHOS) in cancer cells

Ahmed F. Salem, Diana Whitaker‐Menezes, Lin Zhao et al. · Cell Cycle · 2012 · 111 citations · Full text

Life Sciences, Cancer Biology, Oncology +17