A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations

Yiqun Zhang, Patrick Kwok‐Shing Ng, Melanie H. Kucherlapati, +39

Cancer Cell

Tumor BiologyCancer GenomicsPi3k/akt/mtor Pathway AlterationsTumor SuppressorSystems Biology +4

The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers

Leng Han, Lixia Diao, Shuangxing Yu, +21

Cancer Cell

A-to-i Rna EditingTumor BiologyEngineeringGenomic LandscapeMedicine +8

SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression

Zhihu Ding, Chang‐Jiun Wu, Gerald C. Chu, +25

Nature

MedicineProstatic DiseaseCancer BiologyCell BiologySmad4-dependent Barrier Constrains +1

GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer

Kenneth L. Scott, Omar Kabbarah, Mei‐Chih Liang, +16

Nature

Tumor BiologySignaling PathwayMedicineMtor SignallingTumor Suppressor +4

Systematic Functional Annotation of Somatic Mutations in Cancer

Patrick Kwok‐Shing Ng, Jun Li, Kang Jin Jeong, +37

Cancer Cell

Somatic VariantCancer GenomicsSystematic Functional AnnotationCancer GeneticsSystems Biology +3

Intronic miR-211 Assumes the Tumor Suppressive Function of Its Host Gene in Melanoma

Carmit Levy, Mehdi Khaled, Dimitrios Iliopoulos, +14

Molecular Cell

Tumor BiologyTumor Suppressive FunctionMelanomaHost GeneIntronic Mir-211 +8

Integrative Genome Comparison of Primary and Metastatic Melanomas

Omar Kabbarah, Cristina Nogueira, Bin Feng, +14

PLoS ONE

Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer

Han Liang, Lydia W.T. Cheung, Jie Li, +21

Genome Research

EngineeringGeneticsGynecologyTranscriptomics TechnologyEndometrial Cancers +14

A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer

Xinxin Peng, Xiaoyan Xu, Yumeng Wang, +14

Cancer Cell

Proteomic DiversityRna BiologyGene ExpressionMedicineCell Biology +1

Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in <i>RAS</i> mutant cancers

Chaoyang Sun, Yong Fang, Jun‐Jie Yin, +17

Science Translational Medicine