Concepedia

The FTO/miR‐181b‐3p/ARL5B signaling pathway regulates cell migration and invasion in breast cancer

Yuanyuan Xu, Shuang Ye, Nan Zhang, Shuhui Zheng, Huatao Liu, Kewen Zhou, Ling Wang, Yue Cao, Peng Sun, Tinghuai Wang

Cancer Communications · 2020 · 183 citations · 29 references

DOIFull text

Open access

Abstract

Our work demonstrated the carcinogenic activity of FTO in promoting the invasion and migration of breast cancer cells via the FTO/miR-181b-3p/ARL5B signaling pathway.

References

29

Cancer statistics, 2019

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Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

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Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

Kate D. Meyer, Yogesh Saletore, Paul Zumbo et al. · Cell · 2012 · 4.2K citations · Full text

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N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

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FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N 6 -Methyladenosine RNA Demethylase

Zejuan Li, Hengyou Weng, Rui Su et al. · Cancer Cell · 2016 · 1.6K citations · Full text

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