<p>Molecular Imaging of Inflammation in a Mouse Model of Atherosclerosis Using a Zirconium-89-Labeled Probe</p>

Abstract

⁸⁹Zr radiolabeling of Mal-HSA probes resulted in detectable activity in atherosclerotic lesions in aortas of <i>Apoe^-/-</i> mice, as demonstrated by quantitative in vivo PET/MRI. ⁸⁹Zr-Mal-HSA appears to be a promising diagnostic tool for the early identification of macrophage-rich areas of inflammation in atherosclerosis.