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Bariatric surgery reveals a gut-restricted TGR5 agonist with anti-diabetic effects

Snehal N. Chaudhari, David A. Harris, Hassan Aliakbarian, James Luo, Matthew T. Henke, Renuka Subramaniam, Ashley H. Vernon, Ali Tavakkoli, Eric G. Sheu, A. Sloan Devlin

Nature Chemical Biology · 2020 · 142 citations · 34 references

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34

Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist

Sama I. Sayin, Annika Wahlström, Jenny Felin et al. · Cell Metabolism · 2013 · 2.3K citations · Full text

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TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

Charles Thomas, Antimo Gioiello, Lilia G. Noriega et al. · Cell Metabolism · 2009 · 1.8K citations · Full text

, , +10

A G Protein-coupled Receptor Responsive to Bile Acids

Yuji Kawamata, Ryo Fujii, Masaki Hosoya et al. · Journal of Biological Chemistry · 2003 · 1.6K citations · Full text

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Identification of membrane-type receptor for bile acids (M-BAR)

Takaharu Maruyama, Yasuhisa Miyamoto, Takao Nakamura et al. · Biochemical and Biophysical Research Communications · 2002 · 975 citations

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FXR is a molecular target for the effects of vertical sleeve gastrectomy

Karen K. Ryan, Valentina Tremaroli, Christoffer Clemmensen et al. · Nature · 2014 · 919 citations

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