Concepedia

Sustaining Circulating Regulatory T Cell Subset Contributes to the Therapeutic Effect of Paroxetine on Mice With Diabetic Cardiomyopathy

Yongsheng Han, Jiacheng Lai, Juan Tao, Yu Tai, Weijie Zhou, Paipai Guo, Zhen Wang, Manman Wang, Qingtong Wang

Circulation Journal · 2020 · 17 citations · 16 references

DOIFull text

Open access

Abstract

The impaired systolic heart function of DCM mice was effectively improved by paroxetine therapy, partially through restoring the population of circulating Treg cells by targeting the GRK2-PI3K-Akt pathway.

References

16

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