Concepedia

Scutellarein inhibits BLM-mediated pulmonary fibrosis by affecting fibroblast differentiation, proliferation, and apoptosis

Kang Miao, Ting Pan, Yong Mou, Lei Zhang, Weining Xiong, Yongjian Xu, Jun Yu, Yi Wang

Therapeutic Advances in Chronic Disease · 2020 · 56 citations · 27 references

DOIFull text

Open access

Abstract

In general, scutellarein might exert therapeutic effects on pulmonary fibrosis by altering the differentiation, proliferation, and apoptosis of fibroblasts. Although scutellarein has been demonstrated to be safe in mice, further studies are required to investigate the efficacy of scutellarein in patients with IPF.

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