Concepedia

Nanomicelle protects the immune activation effects of Paclitaxel and sensitizes tumors to anti-PD-1 Immunotherapy

Qianmei Yang, Gang Shi, Xiaolei Chen, Yi Lin, Lin Cheng, Qingyuan Jiang, Xi Yan, Ming Jiang, Yiming Li, Hantao Zhang,

Theranostics · 2020 · 79 citations · 37 references

DOIFull text

Open access

Concepts

Abstract

Our results provide systemic insights into the immune-regulation ability of PTX to induce ICD, which acts as an inducer of endogenous vaccines through ICD effects, and also provides an experimental basis for clinical combination therapy with nano-PTX and PD-1 antibodies.

References

37

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Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy

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Marco Idzko, Hamida Hammad, Menno van Nimwegen et al. · Nature Medicine · 2007 · 620 citations

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