LASP1 interacts with N-WASP to activate the Arp2/3 complex and facilitate colorectal cancer metastasis by increasing tumour budding and worsening the pattern of invasion

Global patterns and trends in colorectal cancer incidence and mortality

Melina Arnold, Mónica S. Sierra, Mathieu Laversanne et al. · Gut · 2016 · 5.3K citations · Full text

Medicine, Oncology, Population Health Sciences +17

Annual Report to the Nation on the Status of Cancer, part I: National cancer statistics

Kathleen A. Cronin, Andrew Lake, Susan Scott et al. · Cancer · 2018 · 1.5K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

Isolation of a novel gene mutated in Wiskott-Aldrich syndrome

Jonathan M.J. Derry, Hans D. Ochs, Uta Francke · Cell · 1994 · 1.1K citations

Life Sciences, Genetics, Molecular Genetics +14

N‐WASP, a novel actin‐depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2‐dependent manner downstream of tyrosine kinases.

Hiroaki Miki, Koichi Miura, T Takenawa · The EMBO Journal · 1996 · 661 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Nck and Phosphatidylinositol 4,5-Bisphosphate Synergistically Activate Actin Polymerization through the N-WASP-Arp2/3 Pathway

Rajat Rohatgi, Peter Nollau, Hsin‐Yi Henry Ho et al. · Journal of Biological Chemistry · 2001 · 400 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15