Knockout of the Tachykinin Receptor 1 in the Mdr2−/− (Abcb4−/−) Mouse Model of Primary Sclerosing Cholangitis Reduces Biliary Damage and Liver Fibrosis

Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration

Alexander Raven, Wei‐Yu Lu, Tak Yung Man et al. · Nature · 2017 · 532 citations · Full text

Life Sciences, Cell Biology, Developmental Biology +16

Mdr2 (Abcb4)-/- mice spontaneously develop severe biliary fibrosis via massive dysregulation of pro- and antifibrogenic genes

Yury Popov, Eleonora Patsenker, Peter Fickert et al. · Journal of Hepatology · 2005 · 268 citations

Medicine, Molecular Biology, Pathology +10

Cholangiocyte senescence by way of N-ras activation is a characteristic of primary sclerosing cholangitis

James H. Tabibian, Steven P. O’Hara, Patrick L. Splinter et al. · Hepatology · 2014 · 247 citations · Full text

Medicine, Pathobiology, Pathology +16

Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2 −/− ( Abcb4 −/−) mouse cholangiopathy model by promoting biliary HCO Symbol output

Anna Baghdasaryan, Thierry Claudel, J. Gumhold et al. · Hepatology · 2011 · 215 citations · Full text

Medicine, Molecular Biology, Pharmacology +17

MiR-31 promotes mammary stem cell expansion and breast tumorigenesis by suppressing Wnt signaling antagonists

Cong Lv, Fengyin Li, Xiang Li et al. · Nature Communications · 2017 · 198 citations · Full text

Medicine, Cell Biology, Oncology +17