Steven P. O’Hara

The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs

Yi Zhu, Tamar Tchkonia, Tamar Pirtskhalava et al. · Aging Cell · 2015 · 2.4K citations · Full text

Life Sciences, Cell Biology, Pharmacology +17

A Cellular Micro-RNA, let-7i, Regulates Toll-like Receptor 4 Expression and Contributes to Cholangiocyte Immune Responses against Cryptosporidium parvum Infection

Xian‐Ming Chen, Patrick L. Splinter, Steven P. O’Hara et al. · Journal of Biological Chemistry · 2007 · 485 citations · Full text

Life Sciences, Cell Biology, Infectious Diseases +17

Cholangiocyte senescence by way of N-ras activation is a characteristic of primary sclerosing cholangitis

James H. Tabibian, Steven P. O’Hara, Patrick L. Splinter et al. · Hepatology · 2014 · 247 citations · Full text

Medicine, Pathobiology, Pathology +16

Multiple TLRs Are Expressed in Human Cholangiocytes and Mediate Host Epithelial Defense Responses to <i>Cryptosporidium parvum</i> via Activation of NF-κB

Xian‐Ming Chen, Steven P. O’Hara, Jeremy B. Nelson et al. · The Journal of Immunology · 2005 · 238 citations · Full text

Veterinary Medicine, Infectious Diseases, Pathobiology +12

Absence of the intestinal microbiota exacerbates hepatobiliary disease in a murine model of primary sclerosing cholangitis

James H. Tabibian, Steven P. O’Hara, Christy E. Trussoni et al. · Hepatology · 2015 · 219 citations · Full text

Medicine, Pathobiology, Pathology +17