Science Advances · 2020 · 114 citations · 10 references
PharmacyPharmaceuticsPharmacokineticsDrug DeliveryNanoparticle Drug DeliveryPharmacokinetic ModelingCancer Drug DeliveryCancer NanomedicineNanocarriers For TherapeuticsNanomedicineNanoparticle Delivery SystemsNanoparticle FormulationsCancer NanotherapyMetricsNanoparticle DeliveryNanoparticle Delivery VectorsNanoparticle Drug DistributionNanoparticle PharmacologyPharmacokinetics Of NanocarriersTumor-targeted Drug Delivery
ratio than by %ID in tumor. These results strongly suggest that PK metrics and calculations can influence the interpretation of NP tumor delivery and stress the need to properly validate novel PK metrics against traditional approaches.
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