Concepedia

Targeting SKP2/Bcr-Abl pathway with Diosmetin suppresses chronic myeloid leukemia proliferation

Yuan Liu, Zhenlong Shao, Yuning Liao, Xiaohong Xia, Chuyi Huang, Jinchan He, Tumei Hu, Cuifu Yu, Lili Jiang, Jinbao Liu,

European Journal of Pharmacology · 2020 · 21 citations · 41 references

DOI

Concepts

References

41

Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro

Susan M. Graham, Heather G. Jørgensen, Elaine Allan et al. · Blood · 2002 · 1.2K citations · Full text

, , +13

Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity

Amie S. Corbin, Anupriya Agarwal, Marc Loriaux et al. · Journal of Clinical Investigation · 2010 · 763 citations

, , +17

Bcr/Abl activates transcription of theBcl-X gene through STAT5

Franck Gesbert, James D. Griffin · Blood · 2000 · 241 citations

, , +6

BCR/ABL Regulates Expression of the Cyclin-dependent Kinase Inhibitor p27Kip1 through the Phosphatidylinositol 3-Kinase/AKT Pathway

Franck Gesbert, William R. Sellers, Sabina Signoretti et al. · Journal of Biological Chemistry · 2000 · 224 citations · Full text

, , +17

Success Story of Targeted Therapy in Chronic Myeloid Leukemia: A Population-Based Study of Patients Diagnosed in Sweden From 1973 to 2008

Magnus Björkholm, Lotta Ohm, Sandra Eloranta et al. · Journal of Clinical Oncology · 2011 · 214 citations

, , +13