MicroRNA-responsive release of Cas9/sgRNA from DNA nanoflower for cytosolic protein delivery and enhanced genome editing

Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

Martin Jínek, Fuguo Jiang, David W. Taylor et al. · Science · 2014 · 1.3K citations

Life Sciences, Genetics, Molecular Biology +12

OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma

Pedro P. Medina, Mona J. Nolde, Frank J. Slack · Nature · 2010 · 968 citations

Medicine, Cancer Biology, Oncology +12

Self‐Assembled DNA Nanoclews for the Efficient Delivery of CRISPR–Cas9 for Genome Editing

Wujin Sun, Wenyan Ji, Jordan M. Hall et al. · Angewandte Chemie International Edition · 2015 · 623 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +17

Noncanonical Self-Assembly of Multifunctional DNA Nanoflowers for Biomedical Applications

Guizhi Zhu, Rong Hu, Zilong Zhao et al. · Journal of the American Chemical Society · 2013 · 436 citations · Full text

Natural Sciences, Biotechnology, Materials Science +17

Thermo‐triggered Release of CRISPR‐Cas9 System by Lipid‐Encapsulated Gold Nanoparticles for Tumor Therapy

Peng Wang, Lingmin Zhang, Wenfu Zheng et al. · Angewandte Chemie International Edition · 2017 · 405 citations

Pharmacy, Biotechnology, Oncology +17