Concepedia

Physiological blood–brain transport is impaired with age by a shift in transcytosis

Andrew C. Yang, Marc Y. Stevens, Michelle B. Chen, Davis P. Lee, Daniel Stähli, David Gate, Kévin Contrepois, Winnie Chen, Tal Iram, Lichao Zhang,

Nature · 2020 · 474 citations · 80 references

Open access

Concepts

Life SciencesNeurosciencePhysiologyAgingBiological Transport PhenomenaEndocytosisAge-related PharmacokineticsAge-related Physiologic ChangesAging PhysiologyBiological AgingBlood-brain Barrier BiologyBlood-brain Barrier DysfunctionBlood - Brain Barrier TransportTranscytosis Across The Blood-brain BarrierTranscytosis At The Blood-brain Barrier

References

80

Gene Ontology: tool for the unification of biology

Michael Ashburner, Catherine A. Ball, Judith A. Blake et al. · Nature Genetics · 2000 · 44.6K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +9

Tissue-based map of the human proteome

Mathias Uhlén, Linn Fagerberg, Björn M. Hallström et al. · Science · 2015 · 15.9K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

Jürgen Cox, Matthias Mann · Nature Biotechnology · 2008 · 15.7K citations

Life Sciences, Biochemistry, Mass Spectrometric Analysis +15

Integrating single-cell transcriptomic data across different conditions, technologies, and species

Andrew Butler, Paul Hoffman, Peter Smibert et al. · Nature Biotechnology · 2018 · 14.7K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +14

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β

Jeffrey J. Iliff, Minghuan Wang, Yonghong Liao et al. · Science Translational Medicine · 2012 · 5.6K citations · Full text

Medicine, Neurobiology, Neuroscience +16