Involvement of ROS/NLRP3 Inflammasome Signaling Pathway in Doxorubicin-Induced Cardiotoxicity

Inflammasome Activation of Cardiac Fibroblasts Is Essential for Myocardial Ischemia/Reperfusion Injury

Masanori Kawaguchi, Masafumi Takahashi, Takeki Hata et al. · Circulation · 2011 · 862 citations

Veterinary Medicine, Cardiology, Pathobiology +17

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response

Alberto Baroja‐Mazo, Fatima Martín‐Sánchez, Ana Isabel Gómez Córdoba et al. · Nature Immunology · 2014 · 796 citations

Life Sciences, Cell Biology, Immunology +14

The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse

Eleonora Mezzaroma, Stefano Toldo, Daniela Farkas et al. · Proceedings of the National Academy of Sciences · 2011 · 621 citations

Life Sciences, Cardiology, Pharmacology +16

FNDC5 alleviates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via activating AKT

Xin Zhang, Can Hu, Chun‐Yan Kong et al. · Cell Death and Differentiation · 2019 · 449 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17

Cardiomyocyte-specific IκB kinase (IKK)/NF-κB activation induces reversible inflammatory cardiomyopathy and heart failure

Harald J. Maier, Tobias G. Schips, Astrid Wietelmann et al. · Proceedings of the National Academy of Sciences · 2012 · 172 citations · Full text

Life Sciences, Cardiology, Cell Biology +16