The oxidation of <i>l</i>(−)α-hydroxyglutaric acid in animal tissues

Abstract

oc-HYDROXYGLUTARIC ACID was first recognized as a substrate of the inter- mediary metabolism of animal tissues by Thunberg [1920] who found that it reduced methylene blue in presence of washed frog muscle. But apart from these few scattered observations the dehydrogenation of hydroxyglutaric acid seems to have passed unnoticed.