Concepedia

Interferon-Independent Activities of Mammalian STING Mediate Antiviral Response and Tumor Immune Evasion

Jianjun Wu, Nicole Dobbs, Kun Yang, Nan Yan

Immunity · 2020 · 371 citations · 30 references

DOIFull text

Open access

Concepts

References

30

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

Hiroki Ishikawa, Zhe Ma, Glen N. Barber · Nature · 2009 · 2.7K citations · Full text

, , +14

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation

Siqi Liu, Xin Cai, Jiaxi Wu et al. · Science · 2015 · 1.9K citations

, , +17

Activated STING in a Vascular and Pulmonary Syndrome

Adriana A. de Jesus, Bernadette Marrero, Dan Yang et al. · New England Journal of Medicine · 2014 · 1.4K citations · Full text

, , +14

Autophagy induction via STING trafficking is a primordial function of the cGAS pathway

Xiang Gui, Hui Yang, Tuo Li et al. · Nature · 2019 · 1.3K citations · Full text

, , +14

Targeting STING with covalent small-molecule inhibitors

Simone M. Haag, Muhammet F. Gülen, Luc Reymond et al. · Nature · 2018 · 1.1K citations · Full text

, , +12