Concepedia

Effect of anti‐interleukin‐1 treatment on quality of life in children with colchicine‐resistant familial Mediterranean fever: A single‐center experience

Tuba Kurt, Fatma Aydın, Nilüfer Tekgöz, Müge Sezer, Nermin Uncu, Banu Çelikel Acar

International Journal of Rheumatic Diseases · 2020 · 17 citations · 15 references

DOI

Abstract

Anti-IL-1 treatment is quite effective in children with colchicine-resistant FMF patients, proven with improved AIDAI scores and school attendance rates. In the long term by lowering disease activation even development of amyloidosis may be prevented.

References

15

Criteria for the diagnosis of familial mediterranean fever

Avi Livneh, Pnina Langevitz, Deborah Zemer et al. · Arthritis & Rheumatism · 1997 · 1.5K citations

A new set of criteria for the diagnosis of familial Mediterranean fever in childhood

Fatoş Yalçınkaya, Seza Özen, Zeynep Birsin Özçakar et al. · Lara D. Veeken · 2009 · 512 citations · Full text

Gain-of-Function Pyrin Mutations Induce NLRP3 Protein-Independent Interleukin-1β Activation and Severe Autoinflammation in Mice

Jae Jin Chae, Young-Hun Cho, Geun‐Shik Lee et al. · Immunity · 2011 · 446 citations · Full text

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Validation of the Auto-Inflammatory Diseases Activity Index (AIDAI) for hereditary recurrent fever syndromes

Maryam Piram, Isabelle Koné‐Paut, Helen J. Lachmann et al. · Annals of the Rheumatic Diseases · 2013 · 154 citations · Full text

Efficacy and safety of canakinumab in adolescents and adults with colchicine-resistant familial Mediterranean fever

Ahmet Gül, Huri Özdoğan, Burak Erer et al. · Arthritis Research & Therapy · 2015 · 101 citations · Full text