Simplified low-cost methodology to establish, histologically process and analyze three-dimensional cancer cell spheroid arrays

Spheroid-based drug screen: considerations and practical approach

Juergen Friedrich, Claudia Seidel, Reinhard Ebner et al. · Nature Protocols · 2009 · 1.7K citations

Medicine, Pharmacology, Drug Discovery +3

2D and 3D cell cultures – a comparison of different types of cancer cell cultures

Marta Kapałczyńska, Tomasz Kolenda, Weronika Przybyła et al. · Archives of Medical Science · 2016 · 1.5K citations · Full text

Life Sciences, Cancer Biology, Cell Biology +15

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

Maria Vinci, Sharon Gowan, Frances Boxall et al. · BMC Biology · 2012 · 1K citations · Full text

Medicine, Cell Biology, Oncology +17

Method for generation of homogeneous multicellular tumor spheroids applicable to a wide variety of cell types

Jens M. Kelm, Nicholas Timmins, Catherine J. Brown et al. · Biotechnology and Bioengineering · 2003 · 916 citations

Life Sciences, Bioengineering, Cell Biology +13

Three-dimensional tissue culture based on magnetic cell levitation

Glauco R. Souza, Jennifer R. Molina, Robert M. Raphael et al. · Nature Nanotechnology · 2010 · 654 citations

Engineering, Bioengineering, Biomedical Engineering +14