TH cell diversity and response to dupilumab in patients with atopic dermatitis

Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis

Eric L. Simpson, Thomas Bieber, Emma Guttman‐Yassky et al. · New England Journal of Medicine · 2016 · 2K citations · Full text

Medicine, Dermatology, Immunology +12

Human Blood CXCR5+CD4+ T Cells Are Counterparts of T Follicular Cells and Contain Specific Subsets that Differentially Support Antibody Secretion

Rimpei Morita, Nathalie Schmitt, Salah-Eddine Bentebibel et al. · Immunity · 2011 · 1.6K citations · Full text

Life Sciences, Cell Biology, Immunology +15

Dupilumab Treatment in Adults with Moderate-to-Severe Atopic Dermatitis

Lisa A. Beck, Diamant Thaçi, Jennifer D. Hamilton et al. · New England Journal of Medicine · 2014 · 1.4K citations

Medicine, Dermatology, Immunology +13

Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis

Jennifer D. Hamilton, Mayte Suárez‐Fariñas, Nikhil Dhingra et al. · Journal of Allergy and Clinical Immunology · 2014 · 469 citations · Full text

Medicine, Dermatology, Pharmacology +15

Early pediatric atopic dermatitis shows only a cutaneous lymphocyte antigen (CLA)+ TH2/TH1 cell imbalance, whereas adults acquire CLA+ TH22/TC22 cell subsets

Tali Czarnowicki, Hitokazu Esaki, Juana Gonzalez et al. · Journal of Allergy and Clinical Immunology · 2015 · 205 citations · Full text

Medicine, Dermatology, Immunology +17