Concepedia

Spontaneous Polyploids and Antimutators Compete During the Evolution of <i>Saccharomyces cerevisiae</i> Mutator Cells

Maxwell Tracy, Mitchell Lee, Brady L Hearn, Ian T. Dowsett, Luke C. Thurber, Jason Loo, Anisha M. Loeb, Kent Preston, Miles Tuncel, Niloufar Ghodsian,

Genetics · 2020 · 13 citations · 53 references

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Abstract

Abstract “Mutator” tumor cells that cannot correct DNA replication errors exhibit an extremely high mutation rate that accelerates their evolution. But this gamble puts them at risk for extinction....

References

53

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data

Ethan Cerami, Jianjiong Gao, Uğur Doğrusöz et al. · Cancer Discovery · 2012 · 18.4K citations · Full text

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Comprehensive molecular characterization of human colon and rectal cancer

Nature · 2012 · 8.7K citations · Full text

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Integrated genomic characterization of endometrial carcinoma

Nature · 2013 · 5.8K citations · Full text

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The repertoire of mutational signatures in human cancer

Mi Ni Huang, Alvin Wei Tian Ng, Arnoud Boot et al. · Nature · 2020 · 3.7K citations · Full text

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Getting started with yeast

Fred Sherman · Methods in enzymology on CD-ROM/Methods in enzymology · 2002 · 3.5K citations

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