Concepedia

Mutator Alleles

Mutator Alleles is a genetic construct referring to alleles that increase the genome-wide mutation rate by impairing DNA repair or replication fidelity mechanisms in a heritable manner.

536

Publications

40.4K

Citations

1.8K

Authors

527

Institutions

Publications per year

2017–2026

43

Variants

Mutator Genes

Parents

Publications

536

Mutator phenotype may be required for multistage carcinogenesis.

L A Loeb · PubMed · 1991 · 1.3K citations

, , +11

High Mutation Frequencies Among <i>Escherichia coli</i> and <i>Salmonella</i> Pathogens

J. Eugene LeClerc, Baoguang Li, W L Payne et al. · Science · 1996 · 846 citations

, , +17

Role of mutator alleles in adaptive evolution

François Taddéi, Miroslav Radman, John Maynard-Smith et al. · Nature · 1997 · 710 citations · Full text

, , +14

Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA.

Mark L. Michaels, Cintia Cruz, A.P. Grollman et al. · Proceedings of the National Academy of Sciences · 1992 · 592 citations

, , +14

Microsatellite instability: marker of a mutator phenotype in cancer.

Lawrence A. Loeb · PubMed · 1994 · 552 citations

, , +13

1–5 of 536

Authors

1.8K

  1. RM
    Roel M. Schaaper

    National Institute of Environmental Health Sciences, United States

    12 publications · 731 citations

    12

    h-index

  2. JH
    Jeffrey H Miller

    University of California, Los Angeles, United States

    13 publications · 2K citations

    12

    h-index

  3. EC
    Edward C. Cox

    Princeton University, United States

    11 publications · 1.1K citations

    11

    h-index

  4. TA
    Thomas A. Kunkel

    National Institute of Environmental Health Sciences, United States

    9 publications · 434 citations

    10

    h-index

  5. DS
    D. S. Robertson

    Iowa State University, United States

    9 publications · 501 citations

    9

    h-index

1–5 of 1.8K

Institutions

527

  1. National Institute of Environmental Health Sciences

    Durham, United States

    22 h-index

    73 publications

    3.7K citations

  2. Stanford University

    Stanford, United States

    16 h-index

    30 publications

    2.1K citations

  3. University of Washington

    Seattle, United States

    15 h-index

    84 publications

    8.2K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    15 h-index

    62 publications

    7.6K citations

  5. University of California, Los Angeles

    Los Angeles, United States

    14 h-index

    76 publications

    11.2K citations

  6. Princeton University

    Princeton, United States

    13 h-index

    25 publications

    2.4K citations

  7. Yale University

    New Haven, United States

    13 h-index

    36 publications

    2.8K citations

  8. Université Paris Cité

    Paris, France

    13 h-index

    57 publications

    8.5K citations

1–8 of 527

Venues

  1. Genetics

    65 publications · 4.3K citations

    40

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 48 publications · 7K citations

    39

    h-index

  3. Journal of Bacteriology

    JB · 51 publications · 3.4K citations

    32

    h-index

  4. PubMed

    Repository · 34 publications · 4.2K citations

    23

    h-index

  5. Molecular and General Genetics MGG

    22 publications · 1.2K citations

    19

    h-index

1–5