Publication | Open Access

POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair Status

BiologyGenome InstabilityAllelic VariantGenetic DisorderNatural SciencesGeneticsMutant Allele IdentityDna ReplicationMolecular BiologyGenetic MechanismMolecular GeneticsGenetic VariationMedicineMismatch Repair StatusMutagenesis