Immunotherapy with engineered bacteria by targeting the STING pathway for anti-tumor immunity

STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors

Seng‐Ryong Woo, Mercedes B. Fuertes, Leticia Corrales et al. · Immunity · 2014 · 1.7K citations · Full text

Cancer Immunosurveillance, Innate Immune System, Immunology +8

Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity

Leticia Corrales, Laura Hix Glickman, Sarah M. McWhirter et al. · Cell Reports · 2015 · 1.4K citations · Full text

The toxins of William B. Coley and the treatment of bone and soft-tissue sarcomas.

Edward F. McCarthy · PubMed · 2006 · 750 citations

Radiation Medicine, Tumor Immunology, Malignant Disease +14

The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING

Elie J. Diner, Dara Burdette, Stephen C. Wilson et al. · Cell Reports · 2013 · 732 citations · Full text

STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade

Juan Fu, David B. Kanne, Meredith L. Leong et al. · Science Translational Medicine · 2015 · 681 citations