Concepedia

Publication | Open Access

Role of the GLUT1 Glucose Transporter in Postnatal CNS Angiogenesis and Blood-Brain Barrier Integrity

DOIFull Paper Access

242

Citations

38

References

2020

Year

Koen Veys, Zheng Fan, Moheb Ghobrial, Ann Bouché, Melissa García‐Caballero, Kim Vriens, Nadine V. Conchinha, Aline Seuwen, Felix Schlegel, Tatiane Gorski,
Circulation Research

Abstract

GLUT1 is the main glucose transporter in ECs and becomes uncoupled from glycolysis during quiescence in a Notch-dependent manner. It is crucial for developmental CNS angiogenesis and adult CNS homeostasis but does not affect BBB barrier function.

References

YearCitations

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