Concepedia

SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia

Juan Carlos García‐Cañaveras, Olga Lancho, Gregory S. Ducker, Jonathan M. Ghergurovich, Xincheng Xu, Victoria da Silva-Diz, Sonia Minuzzo, Stefano Indraccolo, Hahn Kim, Daniel Herranz,

Leukemia · 2020 · 127 citations · 43 references

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43

Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells

Wanjuan Yang, Jorge Soares, Patricia Greninger et al. · Nucleic Acids Research · 2012 · 4.3K citations · Full text

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Activating Mutations of <i>NOTCH1</i> in Human T Cell Acute Lymphoblastic Leukemia

Andrew P. Weng, Adolfo A. Ferrando, Woojoong Lee et al. · Science · 2004 · 2.7K citations

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Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation

Mohit Jain, Roland Nilsson, Sonia Sharma et al. · Science · 2012 · 1.5K citations · Full text

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Quantitative flux analysis reveals folate-dependent NADPH production

Jing Fan, Jiangbin Ye, Jurre J. Kamphorst et al. · Nature · 2014 · 1.1K citations · Full text

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Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells

Oliver D.K. Maddocks, Celia R. Berkers, Susan Mason et al. · Nature · 2012 · 1K citations

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