Lewis-acid catalyzed dehydrative [3+2] cycloaddition reaction: A facile synthetic approach to spiro-benzoindoline oxindoles

Nucleophilic ring opening of aziridines

Xiaoyan Hu · Tetrahedron · 2004 · 881 citations

Natural Sciences, Chemistry, Medicinal Chemistry +5

A Library of Spirooxindoles Based on a Stereoselective Three-Component Coupling Reaction

Michael M.‐C. Lo, Christopher S. Neumann, Satoshi Nagayama et al. · Journal of the American Chemical Society · 2004 · 273 citations

Pharmacy, Medicinal Chemistry, Chemical Genetics +15

Epidithiodiketopiperazines Block the Interaction between Hypoxia-inducible Factor-1α (HIF-1α) and p300 by a Zinc Ejection Mechanism

Kristina M. Cook, Stephen T. Hilton, Jasmin Mecinović et al. · Journal of Biological Chemistry · 2009 · 161 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Cyclocarboamination of Alkynes with Aziridines: Synthesis of 2,3-Dihydropyrroles by a Catalyzed Formal [3 + 2] Cycloaddition

Paul A. Wender, Daniel Strand · Journal of the American Chemical Society · 2009 · 148 citations

Natural Sciences, Chemistry, Medicinal Chemistry +11

Spirooxindole-derived morpholine-fused-1,2,3-triazoles: Design, synthesis, cytotoxicity and apoptosis inducing studies

Kishna Ram Senwar, Pankaj Sharma, T. Srinivasa Reddy et al. · European Journal of Medicinal Chemistry · 2015 · 137 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13