ACS Central Science · 2020 · 54 citations · 27 references
Life SciencesBiochemistryChemistryCatalysisEnzyme MechanismEnzymologyBiocatalytic GlycosylationCatalytic MechanismsEnzyme KineticsEnzyme-substrate RecognitionGlycosidic Bond HydrolysisHydrolase CatalysisAnomeric EffectCovalent Enzyme IntermediatesEndoglycosidase ActivityEpoxide FormationEpoxide IntermediatesGlycosidase CatalysisGlycosidasesGlycoside Hydrolysis Mechanisms
O (1.052 ± 0.006) directly implicates nucleophilic participation by the C2-hydroxyl. Collectively, these data substantiate this unprecedented and long-imagined enzymatic mechanism.
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The carbohydrate-active enzymes database (CAZy) in 2013
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Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism
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O-GlcNAcase Uses Substrate-assisted Catalysis
Matthew S. Macauley, Garrett E. Whitworth, Aleksandra W. Debowski et al. · Journal of Biological Chemistry · 2005 · 367 citations · Full text