Concepedia

Dysregulated Sp1/miR-130b-3p/HOXA5 axis contributes to tumor angiogenesis and progression of hepatocellular carcinoma

Yadi Liao, Chenwei Wang, Zhiwen Yang, Wenwu Liu, Yichuan Yuan, Kai Li, Yuanping Zhang, Yongjin Wang, Yunxing Shi, Yuxiong Qiu,

Theranostics · 2020 · 94 citations · 34 references

DOIFull text

Open access

Concepts

Abstract

: This study showed that a dysregulation in the Sp1/miR-130b-3p/HOXA5 axis contributed to HCC progression and angiogenesis, and that HOXA5 can be considered as a promising therapeutic target for treating HCC.

References

34

starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data

Jun-Hao Li, Shun Liu, Hui Zhou et al. · Nucleic Acids Research · 2013 · 6K citations · Full text

, , +16

AASLD guidelines for the treatment of hepatocellular carcinoma

Julie K. Heimbach, Laura Kulik, Richard S. Finn et al. · Hepatology · 2017 · 4.2K citations · Full text

, , +12

Hepatocellular Carcinoma.

Annals of Internal Medicine · 1977 · 2.1K citations

, , +17

PI3K/AKT/mTOR Pathway in Angiogenesis

Jayashree Karar, Amit Maity · Frontiers in Molecular Neuroscience · 2011 · 1.5K citations · Full text

, , +14

Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1

Tomohiro Umezu, Hiroko Tadokoro, Kenko Azuma et al. · Blood · 2014 · 601 citations · Full text

, , +16