Concepedia

circKIF4A promotes tumorogenesis of glioma by targeting miR-139-3p to activate Wnt5a signaling

Longwei Huo, Yafei Wang, Xiaobin Bai, Hu-Lin Zheng, Maode Wang

Molecular Medicine · 2020 · 39 citations · 38 references

DOIFull text

Open access

Abstract

circKIF4A was overexpressed in glioma, and knockdown of circKIF4A suppressed glioma progression via miR-139-3p/Wnt5a axis. The results indicated that circKIF4A may be a potential target for clinical treatment of glioma.

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Viroids are single-stranded covalently closed circular RNA molecules existing as highly base-paired rod-like structures.

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