Sestrin2 overexpression alleviates hydrogen peroxide-induced apoptosis and oxidative stress in retinal ganglion cells by enhancing Nrf2 activation via Keap1 downregulation

p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling

Andrei V. Budanov, Michael Karin · Cell · 2008 · 1.3K citations · Full text

Cell Regulation, Medicine, Apoptosis +7

Cell fate determination in the vertebrate retina.

Constance L. Cepko, Christopher P. Austin, Xian-Jie Yang et al. · Proceedings of the National Academy of Sciences · 1996 · 987 citations · Full text

Retina Change, Ganglion Cell, Photoreceptor Cell +13

Sestrins Activate Nrf2 by Promoting p62-Dependent Autophagic Degradation of Keap1 and Prevent Oxidative Liver Damage

Soo Han Bae, Su Haeng Sung, Sue Young Oh et al. · Cell Metabolism · 2012 · 481 citations · Full text

Inflammation, Reductive Stress, Biochemistry +14

Timing and topography of cell genesis in the rat retina

David Rapaport, Lily Wong, Eric D. Wood et al. · The Journal of Comparative Neurology · 2004 · 383 citations

Identification of a novel stress-responsive gene Hi95 involved in regulation of cell viability

Andrei V. Budanov, Tzipora Shoshani, Alexander Faerman et al. · Oncogene · 2002 · 351 citations

Molecular Regulation, Genetics, Gene Regulation +6