Relationship between changes in the 7-day urticaria activity score after treatment with omalizumab and the responsiveness of basophils to FcωRI stimulation in patients with chronic spontaneous urticaria

Abstract

The weak reactivity of basophils to FcεRI stimulation may not be due to the desensitization of basophils by anti-IgE or anti-FcεRIα autoantibodies. The time to response to omalizumab might differ between BAT-negative and BAT-positive patients with chronic spontaneous urticaria.