Oncogenic Kit signals on endolysosomes and endoplasmic reticulum are essential for neoplastic mast cell proliferation

Yuuki Obata, Shota Toyoshima, Ei Wakamatsu, +4

Nature Communications

PathologyCell ProliferationOncogenic Kit SignalsTumor BiologySignaling Pathway +14

A humanized mouse model to study asthmatic airway inflammation via the human IL-33/IL-13 axis

Ryoji Ito, Shuichiro Maruoka, K. Soda, +15

JCI Insight

Activation of inflammation and resolution pathways of lipid mediators in synovial fluid from patients with severe rheumatoid arthritis compared with severe osteoarthritis

Yutaka Sano, Shota Toyoshima, Yoshimi Miki, +6

Asia Pacific Allergy

The dual regulation of substance P-mediated inflammation via human synovial mast cells in rheumatoid arthritis

Yuki Okamura, Shintaro Mishima, Jun‐ichi Kashiwakura, +6

Allergology International

The spleen is the site where mast cells are induced in the development of food allergy

Shota Toyoshima, Ei Wakamatsu, Yasuo Ishida, +4

International Immunology

Orally desensitized mast cells form a regulatory network with Treg cells for the control of food allergy

Yoshihiro Takasato, Yosuke Kurashima, Masahiro Kiuchi, +20

Mucosal Immunology

miR103a-3p in extracellular vesicles from FcεRI-aggregated human mast cells enhances IL-5 production by group 2 innate lymphoid cells

Shota Toyoshima, Tomomi Sakamoto-Sasaki, Yusuke Kurosawa, +7

Journal of Allergy and Clinical Immunology

InflammationExtracellular VesiclesCytokineGroup 2Immune Cell Development +11

Characterization of human decidual mast cells and establishment of a culture system

Takayuki Matsuno, Shota Toyoshima, Tomomi Sakamoto-Sasaki, +7

Allergology International

Relationship between changes in the 7-day urticaria activity score after treatment with omalizumab and the responsiveness of basophils to FcωRI stimulation in patients with chronic spontaneous urticaria

T. Endo, Shota Toyoshima, Koremasa Hayama, +5

Asia Pacific Allergy

Higher PGD2 production by synovial mast cells from rheumatoid arthritis patients compared with osteoarthritis patients via miR-199a-3p/prostaglandin synthetase 2 axis

Shintaro Mishima, Jun‐ichi Kashiwakura, Shota Toyoshima, +5

Scientific Reports