The landscape of <i>CD28, CD80, CD86, CTLA4</i>, and <i>ICOS</i> DNA methylation in head and neck squamous cell carcinomas

Luka de Vos, Ingela Grünwald, Emma Bawden, Jörn Dietrich, Kathrin Scheckenbach, Constanze Wiek, Romina Zarbl, Friedrich Bootz, Jennifer Landsberg, Dimo Dietrich

Epigenetics · 2020 · 42 citations · 50 references

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Concepts

Abstract

expression levels are epigenetically co-regulated by DNA methylation. This study provides rationale to test their DNA methylation as potential biomarker for prediction of response to CTLA-4 immune checkpoint inhibitors.

References

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