The FcεRIβ homologue, MS4A4A, promotes FcεRI signal transduction and store-operated Ca2+ entry in human mast cells

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

Ole Thastrup, Peter J. Cullen, Bjørn K. Drøbak et al. · Proceedings of the National Academy of Sciences · 1990 · 3.3K citations

Life Sciences, Cell Biology, Pharmacology +15

Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps.

Jonathan Lytton, Marisa M. Westlin, Michael R. Hanley · Journal of Biological Chemistry · 1991 · 1.3K citations · Full text

Life Sciences, Biochemistry, Cell Biology +15

LAT Palmitoylation

Weiguo Zhang, Ronald P. Trible, Lawrence E. Samelson · Immunity · 1998 · 838 citations · Full text

Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcεRI or FcγRI

Arnold S. Kirshenbaum, Cem Akin, Yalin Wu et al. · Leukemia Research · 2003 · 508 citations

Life Sciences, Cell Biology, Immunology +9

Regulation of calcium influx by second messengers in rat mast cells

Reinhold Penner, Gary Matthews, Erwin Neher · Nature · 1988 · 502 citations · Full text

Life Sciences, Cell Biology, Physiology +16