Preferential Perinatal Development of Skin-Homing NK1.1+ Innate Lymphoid Cells for Regulation of Cutaneous Microbiota Colonization

Jie Yang, Katherine H. Restori, Ming Xu, E Song, Luming Zhao, Shaomin Hu, Pingyun Lyu, Wei‐Bei Wang, Na Xiong

iScience · 2020 · 14 citations · 56 references

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Abstract

ILC1s regulate proper microbiota colonization and control the opportunistic pathogen Pseudomonas aeruginosa in neonatal mice. These findings provide insight into the development and function of tissue-specific immune cells at neonatal stages, a critical temporal window for establishment of local tissue immune homeostasis.

References

56