Concepedia

Decoding Psoriasis: Integrated Bioinformatics Approach to Understand Hub Genes and Involved Pathways

Saumya Choudhary, Dibyabhaba Pradhan, Noor Saba Khan, Harpreet Singh, George Thomas, Arun K. Jain

Current Pharmaceutical Design · 2020 · 15 citations · 36 references

DOI

Abstract

The hub genes, genomic altered DEGs and other newly identified differentially dysregulated genes would improve our understanding of psoriasis pathogenesis, moreover, the hub genes could be explored as potential therapeutic targets for psoriasis.

References

36

Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks

Paul Shannon, Andrew Markiel, Owen Ozier et al. · Genome Research · 2003 · 52.1K citations · Full text

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

Guangchuang Yu, Li-Gen Wang, Yanyan Han et al. · OMICS A Journal of Integrative Biology · 2012 · 36K citations · Full text

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STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

Damian Szklarczyk, Annika L. Gable, David Lyon et al. · Nucleic Acids Research · 2018 · 18.4K citations · Full text

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KEGG: new perspectives on genomes, pathways, diseases and drugs

Minoru Kanehisa, Miho Furumichi, Mao Tanabe et al. · Nucleic Acids Research · 2016 · 9K citations · Full text

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affy—analysis of <i>Affymetrix GeneChip</i> data at the probe level

Laurent Gautier, Leslie Cope, Benjamin M. Bolstad et al. · Bioinformatics · 2004 · 5.3K citations · Full text