Concepedia

A bioorthogonal system reveals antitumour immune function of pyroptosis

Qinyang Wang, Yupeng Wang, Jingjin Ding, Chunhong Wang, Xuehan Zhou, Wenqing Gao, Huanwei Huang, Feng Shao, Zhibo Liu

Nature · 2020 · 1.1K citations · 27 references

DOI

Concepts

References

27

Principles of nanoparticle design for overcoming biological barriers to drug delivery

Elvin Blanco, Haifa Shen, Mauro Ferrari · Nature Biotechnology · 2015 · 6.7K citations · Full text

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Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

Jianjin Shi, Yue Zhao, Kun Wang et al. · Nature · 2015 · 6.5K citations

, , +14

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

Nobuhiko Kayagaki, Irma B. Stowe, Bettina L. Lee et al. · Nature · 2015 · 3.7K citations

, , +13

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

Yupeng Wang, Wenqing Gao, Xuyan Shi et al. · Nature · 2017 · 3.2K citations

, , +13

Pore-forming activity and structural autoinhibition of the gasdermin family

Jingjin Ding, Kun Wang, Wang Liu et al. · Nature · 2016 · 2.8K citations

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