Design, synthesis, in vitro and in silico studies of novel 4-oxoquinoline ribonucleoside derivatives as HIV-1 reverse transcriptase inhibitors

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

Garrett M. Morris, Ruth Huey, William Lindstrom et al. · Journal of Computational Chemistry · 2009 · 23.9K citations · Full text

Combining Global and Local Measures for Structure-Based Druggability Predictions

Andrea Volkamer, Daniel Kühn, Thomas Grombacher et al. · Journal of Chemical Information and Modeling · 2011 · 481 citations

The Synthesis of Certain Substituted Quinolines and 5,6-Benzoquinolines

R. Gordon Gould, Walter A. Jacobs · Journal of the American Chemical Society · 1939 · 297 citations

Certain Substituted Quinolines, Derivative (Chemistry), Heterocyclic +8

Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor

Robert Esnouf, Jingshan Ren, Andrew L. Hopkins et al. · Proceedings of the National Academy of Sciences · 1997 · 190 citations · Full text

Metabolic Activation of Nevirapine in Human Liver Microsomes: Dehydrogenation and Inactivation of Cytochrome P450 3A4

Bo Wen, Yuan Chen, William L. Fitch · Drug Metabolism and Disposition · 2009 · 88 citations