Concepedia
Statistics
Publications
14
Citations
1.5K
H-Index
12
Active since
1995
Affiliations
Merck KGaA, Darmstadt (Germany)(Current)
Johannes Gutenberg University Mainz
Institute of Cancer Research
Merck Serono S.p.A. (Italy)
Ono Pharmaceutical (United States)
Thomas Grombacher is an author at Merck KGaA, Darmstadt (Germany) specializing in pharmacology, life sciences, and oncology.
Publications per year
1995–2024
Combining Global and Local Measures for Structure-Based Druggability Predictions
Andrea Volkamer, Daniel Kühn, Thomas Grombacher et al. · Journal of Chemical Information and Modeling · 2011 · 499 citations
Pharmacy, Medicinal Chemistry, Pharmacology +12
Analyzing the Topology of Active Sites: On the Prediction of Pockets and Subpockets
Andrea Volkamer, Axel Griewel, Thomas Grombacher et al. · Journal of Chemical Information and Modeling · 2010 · 303 citations
Life Sciences, Bioinformatics, Biophysics +15
Pharmacologic Inhibitor of DNA-PK, M3814, Potentiates Radiotherapy and Regresses Human Tumors in Mouse Models
Frank T. Zenke, Astrid Zimmermann, Christian Sirrenberg et al. · Molecular Cancer Therapeutics · 2020 · 170 citations
Medicine, Oncology, Pharmacology +9
p53 is involved in regulation of the DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) by DNA damaging agents
Thomas Grombacher, Uta Eichhorn, Bernd Kaina · Oncogene · 1998 · 138 citations
Life Sciences, Genetics, Molecular Biology +12
Induction of the alkyltransferase (MGMT) gene by DNA damaging agents and the glucocorticoid dexamethasone and comparison with the response of base excision repair genes
Thomas Grombacher, Sankar Mitra, Bernd Kaina · Carcinogenesis · 1996 · 119 citations
Life Sciences, Genetics, Molecular Biology +17
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