Thomas Grombacher

Combining Global and Local Measures for Structure-Based Druggability Predictions

Andrea Volkamer, Daniel Kühn, Thomas Grombacher et al. · Journal of Chemical Information and Modeling · 2011 · 481 citations

Analyzing the Topology of Active Sites: On the Prediction of Pockets and Subpockets

Andrea Volkamer, Axel Griewel, Thomas Grombacher et al. · Journal of Chemical Information and Modeling · 2010 · 285 citations

Protein Active Sites, Engineering, Active Sites +24

Pharmacologic Inhibitor of DNA-PK, M3814, Potentiates Radiotherapy and Regresses Human Tumors in Mouse Models

Frank T. Zenke, Astrid Zimmermann, Christian Sirrenberg et al. · Molecular Cancer Therapeutics · 2020 · 158 citations

p53 is involved in regulation of the DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) by DNA damaging agents

Thomas Grombacher, Uta Eichhorn, Bernd Kaina · Oncogene · 1998 · 138 citations

Genome Instability, Dna Damage, Chromatin Remodeling +4

Induction of the alkyltransferase (MGMT) gene by DNA damaging agents and the glucocorticoid dexamethasone and comparison with the response of base excision repair genes

Thomas Grombacher, Sankar Mitra, Bernd Kaina · Carcinogenesis · 1996 · 119 citations