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Hrd1 forms the retrotranslocation pore regulated by auto-ubiquitination and binding of misfolded proteins

Vedran Vasic, Niels Denkert, Claudia Schmidt, Dietmar Riedel, Alexander Stein, Michael Meinecke

Nature Cell Biology · 2020 · 93 citations · 42 references

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42

The effect of sodium ions on the electrical activity of the giant axon of the squid

A. L. Hodgkin, B. Katz · The Journal of Physiology · 1949 · 3.5K citations

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The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

Yihong Ye, Hemmo Meyer, Tom A. Rapoport · Nature · 2001 · 1.1K citations

, , +9

Distinct Ubiquitin-Ligase Complexes Define Convergent Pathways for the Degradation of ER Proteins

Pedro Carvalho, Veit Goder, Tom A. Rapoport · Cell · 2006 · 740 citations · Full text

, , +7

ER Degradation of a Misfolded Luminal Protein by the Cytosolic Ubiquitin-Proteasome Pathway

Mark M. Hiller, Andreas Finger, Markus Schweiger et al. · Science · 1996 · 710 citations

, , +17

Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein.

Randolph Y. Hampton, Richard G. Gardner, Jasper Rine · Molecular Biology of the Cell · 1996 · 595 citations · Full text

, , +17