Concepedia

S-acylation modulates the function of the apical sodium-dependent bile acid transporter in human cells

Alexander L. Ticho, P.K. Malhotra, Christopher R. Manzella, Pradeep K. Dudeja, Seema Saksena, Ravinder K. Gill, Waddah A. Alrefai

Journal of Biological Chemistry · 2020 · 16 citations · 53 references

DOIFull text

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Concepts

Abstract

-acylation is involved in the modulation of ASBT function. These findings underscore the potential for unsaturated fatty acids to reduce ASBT function, which may be useful in disorders in which bile acid toxicity is implicated.

References

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