RAS/RAF mutations and their associations with epigenetic alterations for distinct pathways in Vietnamese colorectal cancer

ESMO consensus guidelines for the management of patients with metastatic colorectal cancer

Eric Van Cutsem, Andrés Cervantes, René Adam et al. · Annals of Oncology · 2016 · 3.3K citations · Full text

Surgical Oncology, Esmo Consensus Guidelines, Gastrointestinal Oncology +9

Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

Wendy De Roock, Bart Claes, David Bernasconi et al. · The Lancet Oncology · 2010 · 2.1K citations

Retrospective Consortium Analysis, Medicine, Pathology +5

ESMO Consensus Guidelines for management of patients with colon and rectal cancer. A personalized approach to clinical decision making

Hans‐Joachim Schmoll, Eric Van Cutsem, Alexander Stein et al. · Annals of Oncology · 2012 · 1.5K citations · Full text

Esmo Consensus Guidelines, Personalized Approach, Gastrointestinal Oncology +9

Genome-scale analysis of aberrant DNA methylation in colorectal cancer

Toshinori Hinoue, Daniel J. Weisenberger, Christopher P.E. Lange et al. · Genome Research · 2011 · 593 citations · Full text

Chromatin, Tumor Biology, Oncology +14

Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.

Manel Esteller, M Toyota, Montse Sánchez‐Céspedes et al. · PubMed · 2000 · 543 citations

Epigenetic Change, Genetics, Dna Methylation +16