Ru‐Catalyzed O‐H Insertion of Sulfoxonium Ylide and Carboxylic Acid to Synthesize α‐Acyloxy Ketones

Abstract

Abstract A Ru‐catalyzed method is developed for the synthesis of α‐acyloxy ketones from sulfoxonium ylide and carboxylic acid. The strategy achieves an excellent selectivity in the presence of 1,10‐phenanthroline as ligand to afford the corresponding product in good yields under simple conditions. The reaction is believed to provide an alternative method to generate ester compounds.