Nucleoside-modified AdoMet analogues for differential methyltransferase targeting

Nicolas V. Cornelissen, Freideriki Michailidou, Fabian Muttach, Kristina Rau, Andrea Rentmeister

Chemical Communications · 2020 · 36 citations · 36 references

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Concepts

Abstract

-modification changed the relative activity of three representative MTases up to 13-fold resulting in discrimination of substrates for the methyl transfer and could also be combined with transfer of allyl and propargyl groups.

References

36