Concepedia

Biomimetic tissue models reveal the role of hyaluronan in melanoma proliferation and invasion

Jiranuwat Sapudom, Khiet-Tam Nguyen, Steve Martin, Tom Wippold, Stephanie Möller, Mathias Schnabelrauch, Ulf Anderegg

Biomaterials Science · 2020 · 22 citations · 44 references

DOIFull text

Open access

Abstract

Biomimetic matrix models demonstrate the role of the size-dependent effect of hyaluronan in melanoma progression and reveal an alternative explanation for<italic>in vivo</italic>findings of hyaluronan dependent melanoma growth.

References

44

Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme

Todd D. Camenisch, Andrew P. Spicer, Tammy Brehm-Gibson et al. · Journal of Clinical Investigation · 2000 · 893 citations · Full text

3D tumour models: novel in vitro approaches to cancer studies

Agata Nyga, Umber Cheema, Marilena Loizidou · Journal of Cell Communication and Signaling · 2011 · 401 citations · Full text

Hyaluronan cross-linking: a protective mechanism in inflammation?

Anthony J. Day, Carol A. de la Motte · Trends in Immunology · 2005 · 329 citations

, , +6

Stroma-Derived Three-Dimensional Matrices Are Necessary and Sufficient to Promote Desmoplastic Differentiation of Normal Fibroblasts

Michael Amatangelo, Daniela Bassi, Andres J. Klein–Szanto et al. · American Journal Of Pathology · 2005 · 238 citations · Full text

, , +10

The over-expression of HAS2, Hyal-2 and CD44 is implicated in the invasiveness of breast cancer

Lishanthi Udabage, Gary R. Brownlee, Susan K. Nilsson et al. · Experimental Cell Research · 2005 · 225 citations

, , +7